【摘要】 目的研究党参的活性成分,为质量标准制订提供依据。方法使用色谱技术,对化学成分进行分离纯化,根据理化常数和波谱数据对化合物的结构进行鉴定。结果从党参的醇提物正丁醇萃取部位分离、鉴定出10个化合物,分别为党参炔苷 (1);丁香苷(2);β-D-葡萄糖正己醇苷(3);β-D-果糖正丁醇苷(4);lobetyolinin(5);京尼平苷(6);色氨酸(7);尿嘧啶(8);3’,4’,5, 9,9’-pentaydroxy-5-4,7’-epoxylignan(9);大黄素(10)。结论化合物4～10为党参属内首次发现。更多还原

【Abstract】 OBJECTIVE To elucidate the active component for the quality evaluation of Rdix Codonopsis.METHODS The compounds were separated with chromatography techniques and their structures were elucidated on the basis of spectroscopic evidences and physiochemical properties. RESULTS Ten compounds were isolated from the n-butanol fraction of the ethanolic extract of Codonopsis pilosula and structurally identified as lobetyolin (1),syringin (2), hexyl-β-D-glucopyrannoside (3), butyl-β-D-fructofurnanoside (4), lobetyolinin (5), geniposide (6), tryptophan (7), uracil (8),3’,4’,5,9,9’- pentaydroxy-5-4,7’ -epoxylignan (9) and emodin (10) , respectively. CONCLUSION Compound 4-10 are isolated from genus Codonopsis for the first time and lobetyolin (Ⅰ) can be chosen for quality evaluation.更多还原