【摘要】 目的完善通脉口服液的质量标准。方法采用薄层色谱法对通脉口服液中丹参酮ⅡA进行定性鉴别,以高效液相色谱法同时测定其中阿魏酸、葛根素的含量。结果样品薄层色谱中,在与丹参对照品、丹参对照药材相应的位置显相同颜色的斑点;阿魏酸、葛根素检测浓度分别在0·0176～0·0880mg/ml(r=0·9999)、0·0088～0·0440mg/ml(r=0·9994)范围内与峰面积积分值线性关系良好;平均加样回收率分别为99·75%(RSD=0·62%)、99·92%(RSD=0·63%)。结论质量控制方法简便、准确,所建标准可用于本品的质量控制。更多还原

【Abstract】 OBJECTIVE:To improve the quality standard of Tongmai oral liquid.METHODS:The tanshinone ⅡA in this medicine was identified qualitatively by TLC and the contents of ferulic acid and puerarin were determined simultaneously by HPLC.RESULTS:In the TLC of the testing samples,the same color spots were noted at the corresponding sites of the reference substance of Radix Salviae Miltiorrhizae and the reference medicinal substances of Radix Salviae Miltiorrhizae.The linear range of ferulic acid and puerarin were 0.0 176～0.0 880 mg/ml(r=0.9 999)and 0.0 088～0.0 440mg/ml(r=0.9 994),respectively.The average recovery were 99.75%(RSD=0.62%)and 99.92%(RSD=0.63%),respectively.CONCLUSION:This method is fast,simple and economical,and suitable for the quality control of Tongmai oral liquid.更多还原