【摘要】 目的本研究旨在评价铝接触对作业工人心血管自主神经功能的影响。方法采用EwingDJ推荐的自主神经功能测试组合对32名铝电解工人和34名正常对照工人进行了测试,测试项目共包括四项内容:ValsalvaManoeuvre心率反应(HR-V)、深呼吸时的心率变化(HR-DB)、即立心率反应(HR-IS)和即立血压反应(BP-IS)。结果铝电解工人的尿铝值(40.08±9.36μg/mg肌酐)明显高于对照组,即立时R-R变化能力Rmax:min(1.21±0.18)、即立血压反应BP-IS(6.56±4.91)均明显低于对照组。多元逐步回归分析表明年龄、接触铝的年数、饮酒、受教育年数从不同方面影响心率和血压变化。结论铝电解作业工人的心血管交感神经和副交感神经调节功能降低,心血管自主神经功能系统也是铝损害的一个靶系统。更多还原

【Abstract】 ObjectiveTo evaluate the adverse effect of aluminum-exposure on workers’ cardiovascular autonomic nervous system. MethodsAutonomic nervous system function test battery recommended by Ewing DJ was conducted on 32 aluminum-exposed workers selected from a aluminum electrolysis plant and 34 healthy reference people come from a flour factory. ResultsUrine Al concentration in aluminum electrolysis workers(40.08±9.36μg/mg creatinine) was significantly higher than that of control group. Rmax:min(1.21±0.18) and BP-IS(6.56±4.91)decreased in aluminum-exposed group compared with those of control group. Multiply regression analysis indicated that age, aluminum-exposure duration, alcohol drinking and education duration affect heart rate and blood pressure. ConclusionAluminum may have adverse effect to sympathetic as well as parasympathetic nervous system. Cardiovascular autonomic nervous system is likely a target system of aluminum detriment.更多还原