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野生及栽培甘草HPLC指纹图谱
Studies on the HPLC Fingerprint of Radix Glycyrrhizae
【摘要】 目的:研究野生及栽培甘草的质量区别。方法:建立野生及栽培甘草的HPLC指纹图谱(Cro-masil ODS色谱柱;0.1%磷酸溶液为流动相;梯度洗脱)并进行对比分析;利用MS/MS技术推测化合物结构。结果:鉴定了部分成分的化学结构;野生与栽培甘草所含成分大部分相同,仅有少量区别;栽培甘草中少数成分随栽培年限不同有所变化。结论:本方法灵敏度高,分析快速、准确,可以为甘草药材内在质量控制提供依据。
【Abstract】 AIM: To study the quality disparities between wild and cultivated licorice root.METHOD: HPLC fingerprint of Radix Glycyrrhizae was established(Cromasil ODS column;0.1% phosphoric acid-acetonitrile as mobile phase;gradient elute,etc);The HPLC fingerprints of wild and cultivated licorice root was compared.RESULTS: Some peaks were identified by MS/MS;The fingerprints of them had lettle difference;The contents of two constituents in cultivated licorice root of different growing years were varied dynamically.CONCLUSION:The method is convenient,accurate and suitable for the quality control of Radix Glycyrrhizae.
- 【文献出处】 中国天然药物 ,Chinese Journal of Natural Medicines , 编辑部邮箱 ,2006年02期
- 【分类号】R284.1
- 【被引频次】27
- 【下载频次】771