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216例糖尿病足感染患者血清超敏C反应蛋白的变化及临床意义

The change of serum highly sensitive C-reactive protein in 216 patients with diabetic foot infection and its clinical significance

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【作者】 王鹏华褚月颉于德民张士明王家驰徐俊丁敏田应芳宋丹常柏

【Author】 WANG Peng-hua,CHU Yue-jie,YU De-min,et al.Department of Diabetic Foot,the Metabolic Disease Hospital,Affiliated to Tianjin Medical University,Tianjin 300070,China

【机构】 天津医科大学代谢病医院足病科天津医科大学代谢病医院足病科 300070300070

【摘要】 目的探讨血清超敏C反应蛋白(hsC-RP)在糖尿病足感染(DFI)患者的变化及临床意义。方法将216例DFI患者分为临床症状典型(D)组和非典型(F)组,测定两组治疗前后的hsC-RP,白细胞(WBC)计数及中性粒细胞百分比(N%)。结果两组患者hsC-RP,治疗后较治疗前明显下降(P<0.01)。结论监测hsC-RP可作为诊断DFI及其转归的敏感指标之一,对于临床症状非典型患者更有临床意义。

【Abstract】 Objective To investigate the change of serum highly sensitive C-reactive protein(hsC-RP) in the patients with diabetic foot infection and its clinical significance.Methods 216(patients) with diabetic foot infection(DFI) were divided into two groups: the typical clinical symptom group(D group)(n=104) and the atypical clinical symptom group(F group)(n=112).hsC-RP,white blood cell(WBC) count,the percentage of neutrophil(N%) were measured before and after treatment.Results After treatment,hsC-RP significantly decreased in D group(16.28±3.48 vs 9.34±2.96 mg/L,P<0.01).hsC-RP significantly decreased in F group(13.56±2.76 vs 8.53±2.34 mg/L,P<0.01).Conclusions Monitoring hsC-RP can be as the sensitive index to diagnose DFI and judge its outcome.It is more significant in the patients with atypical clinical symptom.

【关键词】 糖尿病足,感染C反应蛋白
【Key words】 Diabetic footInfectionC-reactive protein
  • 【文献出处】 中国糖尿病杂志 ,Chinese Journal of Diabetes , 编辑部邮箱 ,2006年06期
  • 【分类号】R587.2
  • 【被引频次】39
  • 【下载频次】317
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