【摘要】 利用SPF鸡胚传代的方法从北京、天津病死鸽的脑组织中分离到两株病毒,研究证实两株病毒能凝集鸡红细胞,且这种凝集效应能被鸡新城疫标准阳性血清所抑制。通过动物回归试验、EID50、MDT、ICPI、IVPI及其他生物学特性试验,证实两分离株均为鸽Ⅰ型副黏病毒中等毒力毒株,分别命名为L18、TJ11株,分离毒株对8周龄鸽有很强的致病性。用2个毒株制备的油乳剂灭活疫苗进行免疫保护实验,结果显示两个分离株之间具有较好的交叉保护性,为该病的疫苗防制奠定了基础。更多还原

【Abstract】 Two Paramyxovirus type Ⅰ(PMV-Ⅰ)virus strains were isolated from dead pigeons using SPF chicken embryos. Two isolates could agglutinate chicken erythrocytes and hemagglutination could be inhibited by antiserum of Newcastle disease virus. The animal regressive research,MDT,ICPI,IVPI and the other biological characteristics tests indicated that the isolates belonged to a mesogenic virus strain of pigeon PMV-Ⅰ,named L18 and TJ11,respectively. Both of them were high pathogenic to 8-week-old pigeons. Further test showed that there was a good cross protection between L18 and TJ11.更多还原