【摘要】 目的探讨我国早产发生的主要危险因素,为预防决策提供依据。方法利用meta分析方法综合国内1994—2005年间关于早产危险因素的分析性研究文献22篇,累计早产4097例,足月产对照11369例。结果各危险因素合并比值比分别为:胎膜早破OR=4.84(95%CI:3.92～5.99);多胎妊娠OR=5.16(95%CI:3.15～8.44);臀位OR=3.27(95%CI:1.90～15.61);前置胎盘OR=6.95(95%CI:4.27～11.32);妊高征OR=2.18(95%CI:1.89～2.52);未进行产前检查OR=4.35(95%CI:2.94～6.44);人工流产史OR=1.01(95%CI:0.97～1.05);产前出血,OR=3.89(95%CI:2.08～7.27);贫血及其他内科合并症OR=3.74(95%CI:2.16～6.50)。结论目前我国孕妇早产的危险因素与早产的联系强度由强到弱依次为胎膜早破、多胎妊娠、臀位、前置胎盘、妊高征、未进行产前检查、产前出血、妊娠合并贫血及其他内科疾病。更多还原

【Abstract】 OBJECTIVE To evaluate the risk factors of prematurity in China and to provide evidence for prevention. METHODS The results of 22 studies on the risk factors of prematruity from 1994-2005 were analyzed synthetically by metaanalysis. RESULTS The pooled OR values(95%CI)of premature rupture of membranes,polycyesis,breech presentation,placenta,gestational hypertension,no antenatal consultations,abactus venter records,antepartum hemorrhage,pregnancy with anaemia or other disease were 4.84(3.92～5.99),5.16(3.15～8.44),3.27(1.90～5.61),6.95(4.27～11.32),2.18(1.89～2.52),4.35(2.94～6.44),1.01(0.97～1.05),3.89(2.08～7.27),3.74(2.16～6.50),respectively. CONCLUTIONS The main risk factors of prematurity in order in China were premature rupture of membranes,polycyesis,breech presentation,placenta, gestational hypertension, no antenatal consultations,antepartum hemorrhage,pregnancy with anaemia or other diseases.更多还原