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辅助生殖技术结局的临床相关因素分析

Pregnant outcome and variables affecting success in IVF/ICSI

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【作者】 巫新春曹云霞丛林魏兆莲周平赵济华李芬章志国张文香

【Author】 WU Xin-Chun,CAO Yun-Xia,CONG Lin,et al.Assisted Reproduction Center,Department of Obstetrics and Gynecology,the First Affiliated Hospital,Anhui Medical University,Hefei 230022,Anhui,China

【机构】 安徽医科大学第一附属医院妇产科生殖医学中心安徽医科大学第一附属医院妇产科生殖医学中心 (安徽合肥)230022(安徽合肥)230022

【摘要】 目的:回顾分析辅助生殖技术(IVF/ICSl)中妊娠结局,并对临床相关因素及其对妊娠结局的影响进行分析。方法:收集我院生殖中心2004年1月1日~6月31日176例患者189个辅助生殖周期治疗的临床资料,进行整理统计和分析。结果:种植率、生化妊娠率及临床妊娠率分别为22.97%、33.53%、30.64%;冻融胚胎移植临床妊娠率23.08%,单周期累计临床妊娠率32.37%;妊娠者较未妊娠者年龄轻(P<0.05);年龄≤35岁组较年龄>35岁组妊娠率高(分别为48.98%和11.11%,P<0.05);妊娠史对治疗结局有一定影响。结论:分析IVF/ICSI中影响妊娠结局的临床相关因素将提高种植率和妊娠率。

【Abstract】 Objective:To analyze the pregnancy outcome of in vitro fertilization(IVF)/intracytoplasmic sperm injection(ICSI) and evaluate the variables affecting embryo transfer success or failure.Methods:A retrospective cohort study was conducted.The population under study consisted of 176 consective fresh embryo transfers and 13 frozen embryo transfers.Results:Implantation and clinical pregnancy rates were 22.97% and 30.64% respectively,and the clinical pregnancy rates of frozen embryo transfer were 23.08% which resulted in a cumulative clinical pregnancy rates per cycle of 32.37%.The pregnancy rates were significantly increased in ≤35 years old group compared to that in >35 years old group(48.98% vs 11.11%,P<0.05).The patients who had historic pregnancy would affect the pregnancy outcome in subsequent IVF.Conclusion:An understanding of variables associated with embryo transfer success will enhance the efficiency of IVF/ICSI by maximizing embryo implantation.

  • 【文献出处】 中国妇幼保健 ,Maternal and Child Health Care of China , 编辑部邮箱 ,2006年21期
  • 【分类号】R714.8
  • 【被引频次】4
  • 【下载频次】259
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