【摘要】 目的:就抽动障碍儿童细胞免疫功能的变化、抗核抗体的产生进行了研究,进一步探讨抽动障碍的病因及发病机制。方法:采用病例对照的实验方法,对30例抽动障碍儿童和30例正常儿童实施了血液抗核抗体、T淋巴细胞亚群的实验室检查。结果:病例组CD 3、CD 4、CD 4/CD 8比值显著低于对照组,病例组抗核抗体(ANA)吸光度值显著高于对照组。结论:抽动障碍儿童存在细胞免疫功能紊乱,即细胞免疫功能降低以及病毒或细菌感染后自身抗体(抗核抗体)的产生。发病前感冒等因素都可能是诱发儿童发生抽动障碍的危险因素。更多还原

【Abstract】 Objective:To study the cellular immune function,anti-ANA(antinuclear antibody)in children for exploring profoundly its etiology mechanism and providing appropriate measures of clinical intervention.Methods:The case control experimental method were conducted. 30 children with TD and 30 normal children were implemented laboratory check about antinuclear antibody(ANA),T lymphocyte subsets in blood.Results:The CD 3,CD 4 and helper/suppressor ratio(CD4/CD8)were significantly lower in case group than those in control group,the absorbency of anti-ANA were significantly higher in case group than that in control group.Conclusion:Children with TD have the abnormity of cellular immune function and the higher concentration of autoantibody.Having a cold recently would be a risky factor resulting in TD.更多还原