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复发性流产患者蜕膜中T淋巴细胞及其亚群变化的研究
Study on the changes of T-lymphocytes and subsets in deciduas with recurrent spontaneous abortion
【摘要】 目的:探讨复发性流产(RSA)与T淋巴细胞免疫功能的关系。方法:采用流式细胞仪与免疫荧光技术相结合,对20例RSA患者和16例正常早孕妇女蜕膜中T淋巴细胞及其亚群进行检测。结果:与对照组相比,RSA组患者蜕膜中总T淋巴细胞及CD4+T淋巴细胞百分率均升高(P(0.05),CD8+T淋巴细胞变化无显著性(P(0.05)。结论:蜕膜中T淋巴细胞亚群失衡可导致复发性流产。
【Abstract】 Objective:To determine the relationship between occurrence of recurrent spontaneous abortion(RSA) and immune function of T -lymphocytes and subsets.Methods:T-lymphocytes and subsets in deciduas of 20 cases with RSA and 16 normal early pregnant women were detected by flow cytometry.Results:The percentage of CD3+ T cells and CD4~+ T cells in deciduas of RSA patients was higher than that in the controls(P﹤0.05),CD8+ T cells had no difference between two groups(P﹥0.05).Conclusion:The imbalance of T-lymphocyte subsets in deciduas are associated with RSA.
【Key words】 Recurrent spontaneous abortion; Decidua; Tlymphocyte subsets; Flow cytometry;
- 【文献出处】 中国妇幼保健 ,Maternal and Child Health Care of China , 编辑部邮箱 ,2006年10期
- 【分类号】R714.21
- 【被引频次】6
- 【下载频次】117