【摘要】 目的探讨丁香酚不同途径给药对昆明鼠的空间学习记忆的影响。方法通过灌胃、嗅觉吸入和鼻腔滴入等不同途径给予丁香酚,用自主活动箱测定小鼠神经兴奋性以及用水迷宫测定小鼠空间学习记忆能力。结果灌胃组、嗅觉吸入组、鼻腔滴入组的自主活动明显高于空白组小鼠自主活动;丁香酚嗅觉吸入组的水迷宫潜伏期明显小于空白组的水迷宫潜伏期。结论丁香酚通过嗅觉吸入的途径能更好地改善小鼠的学习记忆功能。更多还原

【Abstract】 Objective To study the effects learning and memory on Kunming mice through different medication of eugenol. Methods Eugenol was administered through the route of intragastric administration,olfactory inhalation and nasal delivery. Autonomic activity box and water maze was used. Results Autonomic activities was significantly increased in intragastric administration team,olfactory inhalation,nasal delivery groups,and the latency was significantly decreased to find the platform of the eugenol olfactory inhalation group. Conclusion Through olfactory inhalation,eugenol wright improve the learning ability of Kunming mice and memory.更多还原