【摘要】 目的探讨脑梗死与血浆同型半胱氨酸(H cy)水平的关系。方法测定400例脑梗死患者及200例同期住院既往无临床心脑血管病患者的血液总同型半胱氨酸(H cy),维生素B12和叶酸(FA)。结果血液H cy水平,脑梗死组(17.25±7.11)μm o l/L,对照组(10.48±3.01)μm o l/L,差异有显著意义(P<0.01)高同型半胱氨酸在≤40岁患者中危险因素更明显。血清tH cy水平与V itB12及FA水平呈负相关。结论血清tH cy水平升同增加脑梗死的危险度。更多还原

【Abstract】 Objective To investigate the relationship between cerebral infarction and plasma level of homocysteine（Hcy）. Methods The serum level Hcy,folate（FA）and vitaminB₁₂(VitB₁₂)of 400 patients with cerebral infarction and 200 patients without history of clinical cardiovascular diseases and cerebrovascular diseases were measured.Results The serum level of Hcy,in the cerebral infarction group（17.25±7.11μmol/L） was higher than that of control grouop（10.48±3.01μmol/L）.The difference of serum level was significant between cerebral infarction group and control group（P<（0.01））.The risk factor in patients of less than 40 years old was especially higher than control guoup.The level of serum Hcy was negative correlction with that of FA and VitB₁₂.Conclusion The high level of serum Hcy is correlated with risk factor for cerebral infarction.更多还原