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西藏大骨节病与饮水硒关系研究

Study on the relationship between selenium concentrations in drinking water and Kashin-Beck disease in Tibet

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【作者】 李顺江; 杨林生; 王五一; 李永华; 李海蓉; 王丽珍; 西绕若登;

【Author】 LI Shun-jiang, YANG Lin-sheng, WANG Wu-yi, LI Yong-hua, LI Hai-rong, WANG Li-zhen, XIRAO Ruo-deng.The Center of Environment and Health, Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Science, Beijing 100101, China

【机构】 中国科学院地理科学与资源研究所环境与健康中心; 中国科学院地理科学与资源研究所环境与健康中心; 西藏自治区疾病预防控制中心;

【摘要】 目的分析西藏不同地区几类饮用水中的含硒量,探讨大骨节病的分布特征与饮用水中含硒量的关系,寻求西藏地区大骨节病防治的有效措施。方法采集西藏大骨节病病区与非病区的水样,用原子荧光光度计测定水硒,运用SPSS 11.0软件对测定结果进行统计分析。结果西藏地区水硒为(0.23±0.11)μg/L,大骨节病病区和非病区水硒分别为(0.17±0.10)、(0.27±0.11)μg/L,二者比较差异有统计学意义(t=3.03,P< 0.01);沟水含硒量均显著低于河水、溪水、泉水等水源的含硒量(t值分别为-2.16、-2.62、-3.42,P<0.05),几类饮用水中的含硒量由低到高为:沟水<河水<溪水<泉水。结论饮用水中的含硒量与大骨节病病情关系密切,建议通过寻找高硒水源并指导居民选择含硒量较高的水源为饮用水,作为大骨节病防治的辅助措施。

【Abstract】 Objective To analyze selenium concentration of drinking water from different areas in Tibet and to explore into the relationship between selenium concentration of drinking water and the distribution of Kashin Beck disease (KBD), to search an effective method to control and prevent KBD. Methods Water was sampled from disease and non-disease areas in Tibet, and its selenium concentration was measured. Results The averaged selenium concentration of water in Tibet areas was (0.23±0.11 )μg/L, being (0.17±0.10), (0.27±0.11 )μg/L in diseased and non-diseased areas, respectively, with a significant difference (t = 3.03,P < 0.01). Selenium concentration in channel water was significantly lower than that in river water, creek water and spring water(t = - 2.16, - 2.62,- 3.42,P < 0.05). Selenium concentration in drinking water increased in an order from channel water, river water, brook water to spring water. Conclusions There is a close relationship between the selenium concentration in drinking water and the KBD distribution.

【关键词】 大骨节病; 硒; 饮用水;
【Key words】 Kashin-Beck disease; Selenium; Drinking water;
【基金】 国家自然科学基金资助项目(40271009);中国科学院地理科学与资源研究所知识创新基金(CXIOC-A04-06)
  • 【文献出处】 中国地方病学杂志 ,Chinese Journal of Endemiology , 编辑部邮箱 ,2006年04期
  • 【分类号】R684.1
  • 【被引频次】27
  • 【下载频次】293
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