【摘要】 目的探讨食管原发性恶性黑色素瘤的诊断、鉴别诊断及生物学行为。方法报道1例食管原发性恶性黑色素瘤,对其进行临床及病理观察,并复习文献。结果食管原发性恶性黑色素瘤多见于中老年人,常发生于食管中、下段1/3处,大体呈息肉状;免疫组化染色HMB45和S-100(+)。结论食管原发性恶性黑色素瘤是一种罕见肿瘤,对发生于中老年人的食管中、下段息肉样肿物应考虑原发性恶性黑色素瘤之可能。更多还原

【Abstract】 Objective To investigate the diagnosis,different diagnosis and biologic behaviors of primary malignant melanoma of esophagus(PMME).Methods One case of PMME was reported with clinicophathological analysis and review of the literature.Results PMME was often occured in the middle and old,a polypoid tumor in the lower third of esophagus was discoverded,immunohistochemical stains were positive for S-100 protein and HMB-45.Conclusion PMME is a rare neoplasm,and it should be considered as PMME when a polypoid tumor in the lower third of esophagus is observed in the middle-aged man and elderly.更多还原