【摘要】 目的:研究安脑片(石菖蒲)抗癫痫的作用。方法:灌胃给药,观察安脑片对抗苦味毒、硫代氨基脲、最大电休克、青霉素点燃癫痫。结果:安脑片有抗苦味毒和硫代氨基脲引起小鼠惊厥的作用,显著延长惊厥潜伏期,减少惊厥次数,延迟死亡时间;能对抗最大电休克发作,明显降低发作率;能降低癫痫的发作级别,延长发作潜伏期,减少WDS次数。结论:安脑片有显著抗癫痫作用。更多还原

【Abstract】 AIM: To study the antiepileptic effect of Annao Tablet (β-asarone extracted from Acorus tatarinowii schott). METHODS: The medicine was administered orally. The effects were observed in mouse’s convulsion models induced by picrotoxin, thiosemicarbazide, maximal electroshock seizure (MES) and Penicillin G. RESULTS: Annao Tablet had obvious effect against convulsion induced by picrotoxin and thiosemicarbazide, postponed the delitescence, reduced the convulsion times, prolonged the survival time; antagonized MES. The medicine could depress the epileptic degree, postpone spasm latent period, reduce the wet dog shack times. CONCLUSION: Annao Tablet has obvious antiepileptic effect.更多还原