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干燥方法对大黄配方颗粒中蒽醌类成分的影响

Influences of methods of drying on total anthraquinones in Radix et Rhizoma Rhei Dispensing Granules

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【作者】 李敏李晓芳李丽霞张乐刘渝陈丹丹

【Author】 LI Min~1, LI Xiao-fang~1, LI Li-xia~2, ZHANG Le~1, LIU Yu~3, CHEN Dan-dan~1(1.Chengdu University of TCM; Chengdu 610075 Sichuan, China; 2.Chengdu University of TCM Emei Academic, Emei 614201 Sichuan; 3.Sichuan Derentang Traditional Chinese Medicine Co.Ltd. Chengdu 610061 Sichuan, China)

【机构】 成都中医药大学成都中医药大学峨眉学院四川德仁堂中药饮片有限公司成都中医药大学 四川成都610075四川成都610075四川峨眉614201四川成都610061

【摘要】 目的:比较不同干燥方法对大黄配方颗粒中蒽醌类成分的影响。方法:以总蒽醌含量,芦荟大黄素、大黄酸、大黄素、大黄酚和大黄素甲醚的总量为指标,对不同干燥方法进行考察。结果:喷雾条件为浸膏相对密度为1.06~1.10(60°C)进风温度140~150°C,出风温度85~90°C所得的颗粒外观较好,蒽醌类成分破坏最小。结论:大黄配方颗粒最佳的干燥方法是喷雾干燥。

【Abstract】 AIM: To compare the influences of drying methods on Radix et Rhizoma Rhei in Dispensing Granu- les . METHODS: The vaccum and spray methods were studied by determination of total anthraquinones and the sum of aloe-emodin, rhein, emodin, chrysophanol and physcion. RESULTS: When in spray drying conditions re- lative density of extract was 1.06 - 1.10 (60 °C) and entering wind temperature was at 140-150 °C, outlet wind temperature was at 85-90 °C. Radix et Rhizoma Rhei dispensing granules appearance was good, the total anthraquinones was destroyed least. CONCLUSION: Spray drying method for dispensinp granules has superiorily ever vaccum one.

【基金】 国家科技部863项目(2001BA701A40-5)
  • 【文献出处】 中成药 ,Chinese Traditional Patent Medicine , 编辑部邮箱 ,2006年09期
  • 【分类号】TQ461
  • 【被引频次】13
  • 【下载频次】328
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