【摘要】 目的:观察肾康栓对慢性肾衰竭(CRF)湿浊血瘀证的疗效。方法:采用随机、平行、对照方法,治疗组38例患者采用肾康栓塞肛,对照组40例患者应用中药颗粒剂灌肠。观察两组患者治疗前后中医证候积分值、血肌酐(SCr)、内生肌酐清除率(CCr)变化情况。结果:治疗组总有效率81.5%,对照组总有效率为75%。两组患者中医证候积分值、SCr均显著下降(P<0.01或P<0.05),CCr明显升高(P<0.05),但两组相比,无明显差异(P>0.05)。结论:肾康栓可明显改善CRF湿浊血瘀证候的临床表现,降低SCr水平,提高CCr;且疗效与传统中药灌肠疗效法无差别,使用方便。更多还原

【Abstract】 AIM: To observe the curative efficacy of Shenkang Bolt(SKB) in treating chronic renal failure(CRF) with blood silt and damp pathogen syndrome. METHODS: The randomized,parallel and controlled trial were used.38 cases in treatment group were treated with SKB,and 40 cases in control group were clystered with Chinese herbal medicine.The changes of the cumulative scores of traditional Chinese medicine(TCM) syndrome,the levels of serum creatinine(SCr) and creatinine clearance rate(CCr) before and after treatment in both groups were observed. RESULTS: The total effective rate was 81.5% in the treatment group,but 75% in the control group.The scores of TCM syndrome and the levels of SCr were both significantly decreased(P<(0.05) or P<(0.01)) in two groups,CCr was significantly increased(P<(0.05)).There was no difference after treatment in both groups(P>(0.05)). CONCLUSION: SKB can markedly improve the clinical manifestations of CRF with blood silt and damp pathogen syndrome,decrease the levels of SCr,but increase CCr.There was no difference between Chinese herbal clysis and Shenkang Bolt in curative effect,but it is convenent to take Shenkang Bolt.更多还原