【摘要】 目的探讨甲真菌病发病可能的危险因素。方法对175例甲真菌病患者进行1∶1配比的病例对照研究,采用单因素和多因素的条件Logistic回归分析。结果甲真菌病发病与下列9个因素密切相关:足癣(OR=10.502),手癣(OR=9.991),长期用广谱抗生素、皮质类固醇、免疫抑制剂治疗(OR=7.180),潮湿的生活或工作环境(OR=5.167),家族史(OR=2.687),甲外伤(OR=2.668),公用拖鞋、擦脚布、脚盆(OR=2.081),手足多汗(OR=1.955)、勤换鞋袜(OR=0.324)。结论足癣,手癣,长期用广谱抗生素、皮质类固醇、免疫抑制剂治疗,潮湿的生活或工作环境,家族史,甲外伤,公用拖鞋、擦脚布、脚盆,手足多汗是甲真菌病发病的危险因素,勤换鞋袜为甲真菌病的保护因素。更多还原

【Abstract】 Objective To investigate the potential risk factors for onychomycosis.Methods 175 cases with onychomycosis were conducted by a 1∶1 matched case-control study.Data were analyzed by a single-factor and multifactor conditional logistic regress analysis.Results Multifactor conditional logistic regression model indicated that the episode of onychomycosis were significantly correlated with tinea pedis(OR=10.502),tinea manus(OR=9.991),using broad-spectrum antibiotic,corticosteroid and immuno-suppressive drugs for a long time(OR=7.180),the wet environment of living and work(OR=5.167),family history(OR=2.687),nail trauma(OR=2.668),public using slippers,wipe feet cloth and feet-basin(OR=2.081),extremity hyperhidrosis(OR=1.955),changing footgear frequently(OR=0.324).Conclusion Tinea pedis,tinea manus,using broad-spectrum antibiotic,corticosteroid and immuno-suppressive drugs for a long time,the wet environment of living and work,family history,nail trauma,public using slippers,wipe feet cloth and feet-basin,extremity hyperhidrosis were risk factors for onychomycosis;changing footgear frequently was protective factor.更多还原