【摘要】 目的:通过流行病学方法探索抗性淀粉是否为大肠癌的保护因素,为大肠癌的饮食防治提供依据。方法:对山东省150例大肠癌患者及300名社区健康对照者进行一般情况、疾病史、营养“K-A-P”模式及膳食频率调查,利用统计软件SPSS12.0对资料进行单因素分析、多因素非条件Logistic回归分析。结果:有10个因素进入了最终的模型,其中抗性淀粉偏回归系数βi=-1.570(OR=0.208)是大肠癌的保护因素;以0～4g/d为参照进行χ2趋势检验,其余各级的OR值分别为0.95,0.71,0.56,0.27,随着抗性淀粉摄入量的增加而递减,呈明显的剂量反应关系。结论:日常膳食中抗性淀粉含量高的薯类、谷类及富含膳食纤维的蔬菜水果对大肠癌具有预防作用。更多还原

【Abstract】 Objective: To determine the substantial contribution of resistant starch (RS) to disease prevention via epidemiological method. Methods: The uniformed questionnaire included genetic condition, alimentary illness, and food frequency questionnaire. Data of one hundred and fifty colorectal cancer patients and three hundred healthy residents were collected. Unconditional logistic regression was used to find out the primary risk factors of colorectal cancer. Results: RS came into the final regressive equation as a protective factor. The partial regression coefficient of RS was -1.570(odd ratio=0.208), and the dose-response relationship between RS intake and colorectal cancer existed. The average daily RS intake of case was significantly (P<0.05) lower than healthy persons. Conclusion: RS as an ingredient in crude grain food will greatly contribute to its availability in disease prevention.更多还原