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糖皮质激素在鼻窦内镜手术围手术期的应用及疗效观察

Application and efficacy of glucocorticosteroids for perioperative chronic sinusitis and nasal polyps

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【作者】 吕化王宗保梅桢峰

【Author】 LV Hua,WANG Zong-bao,MEI Zhen-feng ( Department of Otolaryngology, Huoshan People’s Hospital, Huoshan Anhui 237200, China)

【机构】 安徽省霍山县人民医院耳鼻喉科安徽省立医院耳鼻喉科 安徽霍山237200安徽霍山237200安徽合肥230001

【摘要】 目的总结糖皮质激素在鼻窦内镜手术围手术期的应用及疗效。方法对因慢性鼻鼻窦炎、鼻息肉接受鼻内镜手术、随访半年以上120例患者是否应用激素,对比观察总结其疗法。结果术前、术后全身及局部均用激素与不用激素的患者相比,疗效提高,患者复发率降低,差异有显著性(P<0.05)。结论围手术期应用激素,能良好控制临床症状,提高治愈率;并有效延缓和减少复发。

【Abstract】 Objective To observe the effect of glucocorticosteroids on perioperative chronic sinusitis and nasal polyps. Methods A total of 120 patients with chronic sinusitis and nasal polyps were divided into two groups randomly. In the first group the patients received routine treatment; while the second group received routine therapy plus local and systemic application of glucocorticosteroids. Results During the follow-up from 6 to 24 months, those administered glucocorticosteroids exhibited better effective result and lower recurrence,and the differences were significant in comparison with those without glucocorticosteroids administration(P<0.05).Conclusion Glucocorticosteroids applied in perioperative sinusitis and nasal polyps has an affirmative efficacy. It can effectively attenuate clinical symptoms, meliorate cure rate, and retard or reduce recurrence.

【关键词】 鼻窦炎鼻息肉内镜术糖皮质激素
【Key words】 SinusitisNasal polypsEndoscopyGlucocorticosteroids
  • 【文献出处】 实用医院临床杂志 ,Practical Journal of Clinical Medicine , 编辑部邮箱 ,2006年05期
  • 【分类号】R765.9
  • 【下载频次】80
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