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盐酸吗啡缓释片治疗晚期癌症疼痛102例

Morphine Hydrochloride Sustained-release Tablets for Treating Cancer Pain in 102 Cases

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【作者】 何文富张茂雷玥婷

【Author】 He Wenfu,Zhang Mao,Lei Yueting(Department of Pharmacy,Yibin First People’ s Hospital of Sichuan Province,Yibin,Sichuan,China 644000)

【机构】 四川省宜宾市第一人民医院药剂科四川省宜宾市第一人民医院药剂科 四川宜宾644000四川宜宾644000

【摘要】 目的观察盐酸吗啡缓释片对晚期癌症的镇痛效果。方法对102例中、重度癌痛患者进行治疗,盐酸吗啡缓释片开始剂量为30mg,每12h服药1次,在用药的过程中根据疼痛缓解程度来调整剂量。结果102例显效68例(66.7%),有效29例(28.4%),无效5例(4.9%),总有效率为95.1%。结论盐酸吗啡缓释片治疗癌症疼痛疗效显著,毒副反应轻,安全可行。

【Abstract】 Objective To observe the analgesic effect of morphine hydrochloride sustained-release tablets on cancer patients at late stage.Methods 102 patients with moderate and severe pain were treated with morphine hydrochloride sustained-release tablets whose beginning usage was 30 mg/12 h,and the dosage was adjusted individually according to the analgesic effect.Results 67%(68 patients)obtained obvious effect,28%(29 patients)got partial effect and 5%(5 patients)showed no effect.The total effective rate was 95%.Conclusion Morphine hydrochloride sustained-release tablets have a significant therapeutic effect on the cancer pain with lower side effect of toxicity and higher safety.

  • 【文献出处】 中国药业 ,China Pharmaceuticals , 编辑部邮箱 ,2006年12期
  • 【分类号】R730.5
  • 【被引频次】3
  • 【下载频次】52
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