【摘要】 目的探讨红细胞中间脆性(MCF)操作方法简化的可靠性以及在贫血诊断中的应用。方法对42例正常对照,44例贫血进行MCF测定,并测定其他血液学指标与46例缺铁性贫血的血液学指标进行对比分析。结果正常对照组的MCF4.21±0.18与病例组的MCF3.53±0.20有极显著性差异(P<0.001)。血液学指标(MCV、MCH、MCHC、RDW):病例组和缺铁性贫血组与对照组有极显著性差异(P<0.001),病例组与缺铁性贫血组无显著性差异(P>0.05)。结论红细胞中间脆性结合其他血液学指标对筛查地中海贫血和诊断缺铁性贫血有重要意义。更多还原

【Abstract】 Objective To estimate the reliability of simplified method for detecting MCF and the clinical application in diagnosis for anemia. Methods MCF of 42 healthy individuals and 44 anemia patients were detected. Other blood indexes were estimated and compared with 46 iron-deficiency anemia patients. Results There was significant difference(P<0.001) between the control group(4.21±0.18) and the anemia patients(3.53±0.20).The difference in blood indexes between two anemia groups and the control group was statistically significent(P <0.001),but the two anemia groups had no difference(P >0.05).Conclusions MCF combined with other blood indexes can screen thalassemia and diagnose iron-deficiency anemia.更多还原