【摘要】 目的探讨在传统正规疗法基础上加用卡托普利和小剂量美托洛尔对慢性充血性心力衰竭的疗效。方法按治疗情况将218例分为4组,Ⅰ组(传统正规疗法),Ⅱ组(Ⅰ组加卡托普利),Ⅲ组(Ⅱ组加美托洛尔),Ⅳ组(非正规疗法)。观察治疗前后心功能变化和跟踪2年内因心源性死亡情况。结果Ⅰ组、Ⅱ组和Ⅲ组的显效率(分别为53.06%、59.02%和57.53%)和总有效率(分别为93.88、96.72%和98.63%)均高于Ⅳ组(显效率0.00%,总有效率28.57%)。2年内因心源性死亡情况:Ⅰ组21.95%,Ⅱ组12.50%,Ⅲ组6.15%。结论传统正规疗法能迅速缓解心力衰竭的症状,缩短患者住院时间;卡托普利和小剂量美托洛尔联合治疗慢性充血性心力衰竭其作用具有协同性,且能明显降低心源性死亡率。更多还原

【Abstract】 Objective To explore the therapeutic effect for captopril and small-does of metoprolol in addition to tradition normal therapeutics on chronic congestive heart failure.Methods 218 patients were allocated to 4 groups according to therapy,Ⅰgroup(tradition normal therapeutics),Ⅱgroup(Ⅰgroup+ captopril),Ⅲgroup (Ⅱgroup+ metoprolol),Ⅳgroup (non- normal therapeutics).To observe the change of heart function in 4 groups before and after treatment,and follow-up the death of heart in two years.Results The markedly effective rate(53.06%、59.02%、57.53%) and the total effective rate (93.88%、96.72%、98.63%) were higher in Ⅰ, Ⅱ and Ⅲ group than in Ⅳ group (markedly effective rate 0.00%,total effective rate 28.57%).The death rate of heart in two years:Ⅰgroup 21.95%,Ⅱgroup 12.50%,Ⅲgroup 6.15%.Conclusion The tradition normal therapeutics can alleviate the symptom of heart failure,shorten time of the sufferer being in hospital;The captopril combined with small-does of metoprolol treating chronic congestive heart failure, which had synergism, and reduced The death rate of heart desease disease markedly.更多还原