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TUR-Bt联合TVBT加吡柔比星灌注治疗膀胱肿瘤疗效观察

Clinical Observation of TUR-Bt and TVBT Combined with Intravesical Instillation of THP for Treatment of Bladder Cancer

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【作者】 张龙涂仁泉肖跃林黄承智

【Author】 ZHANG Long,TU Renquan,XIAO Yuelin,et al.Department of Urology,Ji’an Central Hospital,Jiangxi Province 343000

【机构】 江西省吉安市中心人民医院泌尿外科江西省吉安市中心人民医院泌尿外科 343000343000

【摘要】 目的:探讨经尿道膀胱肿瘤电切术(TUR-Bt)联合经尿道膀胱肿瘤汽化电切术(TVBT)治疗膀胱肿瘤及术后膀胱内灌注吡柔比星(THP)的方法及疗效。方法:采用TUR-Bt联合TVBT及术后行膀胱内灌注THP治疗膀胱肿瘤。结果:22例膀胱肿瘤均一次切除,1例膀胱穿孔改开放手术;平均手术时间:单发瘤20min,多发瘤50min;术后留置尿管4~6d,术后平均住院7d;THP膀胱灌注每周1次,共8周,以后每月1次,连用8个月;随访3个月~4年,无一例复发。结论:TUR-Bt联合TVBT及术后THP灌注治疗膀胱肿瘤,具有操作简单、出血少、并发症少、复发率低、安全性高等优点,且疗效满意。

【Abstract】 Objective:To evaluate the method and effect of transurethral resection of bladder tumor(TUR-Bt) and transurethral vaporization of bladder tumor(TVBT) combined with intravesical instillation of pirarubicin(THP) for treatment of bladder cancer.Methods: The bladder cancer was treated with TUR-Bt and TVBT combined with intravesical instillation of THP after operation.Results: 22 cases were operated successfully first time,only 1 case was treated by partial cystectomy;THP was instilled into bladder,then stayed for 60~120 min.In the following eight weeks,intravesical instillation of THP was administered once a week.After eight weeks,it was done once a month for eight months.Metastases did not found after operation during follow-up of 3 months to 48 months.Conclusion: TUR-Bt,TVBT and THP of intravesical instillation,with simplicity in maneuver,less bleeding and fewer complications,are the safe and effective way in the treatment of bladder cancer.

  • 【文献出处】 医学理论与实践 ,The Journal of Medical Theory and Practice , 编辑部邮箱 ,2006年12期
  • 【分类号】R737.14
  • 【被引频次】1
  • 【下载频次】19
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