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离子导入经皮给药系统
Transdermal Iontophoretic Delivery System
【摘要】 综述了离子导入技术的基本组成、促渗机制、影响因素及应用前景。离子导入技术可有效提高药物的经皮渗透性,该技术扩大了经皮给药系统的研究范围,其对多肽和蛋白质等大分子药物的透皮促渗作用日益受到关注。
【Abstract】 Transdermal iontophoretic technology can effectively increase the drug permeability through skin.This technology can enlarge the scope of transdermal delivery system,especially promote transdermal permeation of peptides and proteins.Composition,iontophoretic transport mechanisms,effects and applications of this technology were reviewed.
【关键词】 离子导入技术;
经皮给药系统;
影响因素;
应用;
【Key words】 Iontophoretic technology; Transdermal drug delivery system; Effects; Applications;
【Key words】 Iontophoretic technology; Transdermal drug delivery system; Effects; Applications;
- 【文献出处】 药学进展 ,Progress in Pharmaceutical Sciences , 编辑部邮箱 ,2006年06期
- 【分类号】R94
- 【被引频次】41
- 【下载频次】968