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一种新型的生物材料:自装配多肽水凝胶的研究和应用
(Research and Application of A Novel Biomaterial: Self-Assembling Peptide Hydrogel)
【摘要】 分子的自装配是自然界中一种普遍存在的现象。一些具备亲水性和疏水性氨基酸残基交替和离子自身互补两种特征的肽段能通过这种自装配作用形成纳米纤维进而形成可见的膜结构。这种膜具有很好的稳定性,能使细胞在其上附着、生长和分化,从而为组织修复、组织工程提供了一个极有前景的生物材料。
【Abstract】 Self-assembly of molecules is a ubiquitous phenomenon in the nature.Some peptides,which are characterized by both amino acid sequences of alternating hydrophobic and hydrophilic side groups and ionic self-complementary,can form the nanofibers,and then,form the macromembrane.This novel biomaterial shows good stability,and is a scaffold for attachment,growth and differentiation of cells.It is a prospective biomaterial for tissue repair and tissue engineering.
- 【文献出处】 药物生物技术 ,Pharmaceutical Biotechnology , 编辑部邮箱 ,2006年06期
- 【分类号】R318.08
- 【被引频次】4
- 【下载频次】381