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破伤风抗毒素致过敏性休克68例文献分析

Analysis of 68 Cases of Tetanus Antitoxin-induced Allergic Shock

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【作者】 王川平王昕孙莉

【Author】 Wang Chuanping,Wang xin,Sun Li Department of Pharmacy,The Second Hospital of HeBei Medical University,ShiJiaZhuang 050000,P. R. China

【机构】 河北医科大学第二医院药剂科河北医科大学第二医院药剂科 石家庄050000石家庄050000

【摘要】 目的:探讨破伤风抗毒素致过敏性休克的特点和规律。方法:检索中文医药卫生期刊1994年-2004年12月报道的破伤风抗毒素致过敏性休克个案,并进行统计分析。结果:破伤风抗毒素致过敏性休克,主要发生在用药后30 min以內,男性多于女性。结论:用药前应询问过敏史,严格用药指征,观察用药后反应,方能确保用药安全。

【Abstract】 Objective:To probe into the characteristics and regularities of Tetanus antitoxin - induced allergic shock. Method:The case reports of Tetanus antitoxin-induced allergic shock published in Chinese medical periodicals during the period of 1994 to 2004 were collected and analyzed. Result:The tetanus antitoxin - induced allergic shock occurred mostly within 30 minutes, and the male cases outnumbered the female cases. Conclusion:Allergic history should be taken in detail before the use; the indications of drug use, strictly controlled and the ADRs, observed so as to ensure the safe use of drugs.

  • 【文献出处】 药物流行病学杂志 ,Chinese Journal of Pharmacoepidemiology , 编辑部邮箱 ,2006年02期
  • 【分类号】R593.1
  • 【被引频次】5
  • 【下载频次】59
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