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老年冠心病、脑梗死患者血清同型半胱氨酸与血糖、脂蛋白、血尿酸之间的关系
Study on the relationship between serum homocysteinemia and the level of serum uric acid,blood glucose,lipoproteins in aged patients with coronary heart disease and stroke
【摘要】 目的探讨老年冠心病、脑梗死患者血清同型半胱氨酸(Hcy)与空腹血糖(FBG)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)、脂蛋白[Lp(a)]、尿酸(UA)的关系。方法测定107例住院老年冠心病和脑梗死患者血清Hcy、FBG、TC、TG、HDL-C、LDL-C、LP(a)、UA等指标,并根据Hcy升高与否分为两组,比较两组FBG、TC、TG、HDL-C、LDL-C、LP(a)、UA的数值。结果Hcy升高组(A组)患者FBG、LP(a)、UA高于Hcy正常组(B组)。A组:FBG(5.51±1.30)mmol/L,TC(4.15±0.71)mmol/L,TG(1.39±1.06)mmol/L,HDL-C(1.08±0.32)mmol/L,LDL-C(2.47±0.73)mmol/L,Lp(a)(34.67±4.08)mg/dl,UA(374.11±9.87)μmol/L。B组:FBG(4.44±0.71)mmol/L,TC(4.03±1.89)mmol/L,TG(1.22±0.76)mmol/L,HDL-C(1.12±0.36)mmol/L,LDL-C(2.35±0.60)mmol/L,LP(a)(24.09±3.93)mg/dl,UA(326.79±11.96)μmol/L。两组间:FBG、LP(a)、UA差异有统计学意义(P<0.05);两组间:TC、TG、HDL-C、LDL-C差异无统计学意义(P>0.05)。结论FBG、LP(a)、UA与血清Hcy密切相关。
【Abstract】 Objective To investigate the relationship of serun homocysteinemia (Hcy) and fasting blood glucose (FBG) ,lipoproteins [TC,TG,HDL-C,LDL-C,LP(a)], serum uric acid(UA) in aged patients with coronary heart disease and stroke. Methods The concentration of serum Hcy, FBG, TC, TG, HDL-C, LDL-C, LP(a) and UA were tested in 107 patients, and according to Hcy value,the patients were divided into two groups(Group A, 52 cases, Hcy>15.6 μmol/L. Group B, 55 cases, Hcy≤15.6 μmol/L). The Hcy, FBG, TC, TG, HDL-C, LDL-C, LP(a) and UA of both groups were compared. Results The concentration of FBG,LP(a) and UA of group A was higher than that of group B (P<0.05).The level, of TC,TG,HDLc and LDL-C hadn’t difference between the group A and group B. Conclusion The level of UA, FBG and LP(a)was related to serum Hcy.
【Key words】 Homocysteinemia; Coronary heart disease; Stroke; Blood glucose; Lipoproteins; Serum uric acid;
- 【文献出处】 中国医师进修杂志 ,Chinese Journal of Postgraduates of Medicine , 编辑部邮箱 ,2006年12期
- 【分类号】R541.4;R743.33
- 【被引频次】18
- 【下载频次】149