【摘要】 目的:选择麦滋林口腔溃疡膜的最佳处方,并观察临床疗效。方法:采用正交试验法,以药膜外观、粘性、溶解性为指标进行评分。将108例患者随机分为2组,治疗组58例,用麦滋林口腔溃疡膜治疗;对照组50例,用洗必泰口腔含漱液治疗。结果:本膜剂成膜最佳处方聚乙烯醇PVA1750 PVA17-88羧甲基纤维素钠(CMC-Na)为1%3%4%。治疗组有效率89.7%,对照组有效率52%(P<0.05)。结论:本膜剂配方合理,疗效确切。更多还原

【Abstract】 AIM:To choose the best formulation of marzulene-S grranuls oral membrane and to evaluate the clinical effects.METHODS: Orthogonal method was used for studying.Take the appearance,viscidity and dissolubility of the oral membrane as the indexes of scoring 108 cases of patients were chosen and divided into two groups randomly.58 case were treated with marzulene-S grranuls oral membrane and 50 cases were treated with gargarisma chlorhexidine as the control group.RESULTS: The best prescription is sodium carboxymethyl cellulose 4%,polyvinyl alcohol₁₇₅₀ 1% and polyvinyl alcohol_17-88 3%.CONCLUSION: The design of the formulation is reasonable and the clinical effect was satisfactory.更多还原