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热毒宁注射液治疗急性上呼吸道感染的临床研究
Clinical observation of Reduning injection in treatment of patients with acute upper respiratory tract infections
【摘要】 目的:评价热毒宁注射液治疗急性上呼吸道感染外感风热证的疗效和安全性。方法:71例急性上呼吸道感染病人随机分为2组,试验组给予热毒宁注射液治疗,20 ml.次.d-1,静脉滴注;对照组给予清开灵注射液治疗,1次.d-1,每次30 ml,静脉滴注。3 d为一个疗程。结果:治疗d 3试验组总体疗效优于对照组(98.08%,94.13%,P<0.01)。治疗d 3试验组中医证候疗效优于对照组(98.07%,94.11%,P<0.05)。未见明显的毒副作用和不良反应症状。结论:用药3 d后热毒宁注射液治疗急性上呼吸道感染外感风热证的疗效优于清开灵注射液,并且安全性良好。
【Abstract】 AIM: To evaluate the efficacy and safety of Reduning injection in treating acute upper respiratory tract infections.METHODS: Seventy-one patients were randomly assigned to two groups.Fifty-three patients in trial group were administrated with Redunimg injection 20 ml,iv gtt,qd,while the other in control group were administrated with Qingkailing injection 30ml,iv gtt,qd.The period of treatment was 3 d for each group.RESULTS: On d 3 after treatment,the total clinical effective rate were 98% in the trial group and 94% in the control group with significant difference between two groups(P<(0.01)),while the total effective rate of Chinese traditional medical symptoms were 98% in the trial group and 94% in the control group with significant difference between two groups(P<(0.05)).In trial and control groups no adverse reactions was found.CONCLUSION: Reduning injection is an effective and safe agent in treatment of patients with acute upper respiratory tract infections.
【Key words】 respiratory tract infections; respiratory system agents; safety; randomized controlled trials; drug evaluation; Reduning injection;
- 【文献出处】 中国临床药理学与治疗学 ,Chinese Journal of Clinical Pharmacology and Therapeutics , 编辑部邮箱 ,2006年04期
- 【分类号】R259
- 【被引频次】141
- 【下载频次】661