【摘要】 目的用DTL电极测量我国正常人视网膜电图的明视负波反应(PhNR)的正常值,探讨正常人PhNR的特征。方法应用美国ESPION视觉电生理仪及一次性使用的DTL电极测量我国正常人65例(112眼)的PhNR。全视野刺激器由LED发出光源,选用蓝色背景光(亮度为10cd/m2),刺激光为红色(刺激光强度分别为1、5cd.s/m2和7cd.s/m2)。按10岁一年龄组分组统计PhNR的振幅和潜伏期。结果经统计学分析,将年龄组间无显著统计学差异的组作合并后,分成<50岁和≥50岁两个年龄组。这两组的正常振幅值在1、5cd.s/m2和7cd.s/m2时分别为(-38.94±10.21)μV和(-32.41±7.76)μV,(-38.51±10.97)μV和(-34.52±8.90)μV,(-38.62±9.98)μV和(-33.96±9.81)μV,正常潜伏值分别为(65.83±4.06)ms和(69.86±5.68)ms,(66.17±6.48)ms和(71.33±4.90)ms,(65.81±6.71)ms和(70.40±4.61)ms,表明两个年龄组的振幅和潜伏值均有显著统计学差异。结论一次性DTL电极可防止交叉感染。研究确定了按相关年龄分组的我国正常人PhNR的正常值。更多还原

【Abstract】 ObjectiveTo test normal values of photopic negative response (PhNR) of electroretinogram (ERG) with DTL electrode in normal Chinese subjects and to evaluate the characteristic of PhNR.MethodsERGs were recorded on 65 normal subjects (112 eyes) aged 21-76 years using disposable DTL electrodes at full-field ganzfeld brief red flashes on a blue background (luminance of 10 cd/m 2 ).Stimulus flashes of different intensity (1cd·s/m 2 ,5cd·s/m 2 and 7cd·s/m 2 ) were generated by light emitting diodes (LEDs).The amplitudes and latencies of PhNR with age were analyzed.ResultsThe data were divided into <50 years group and ≥50 years group after statistical analysis.The mean latencies in the <50 years group was 65.83±4.06ms,66.17±6.48ms and 65.81±6.71ms at 1,5 and 7 cd·s/m2 respectively which was statistically significant different from that ≥50 years group(69.86±5.68ms,71.33 ± 4.90ms and 70.40±4.61ms,respectively)(P<0.001).Mean amplitude of <50 years group was significantly higher than that of ≥50 years group at different stimulus intensities ( -38.94 ± 10.21μV,-38.51± 10.97μV,-38.62± 9.98μV vs-32.41± 7.76μV,-34.52±8.90μV,-33.96± 9.81μV,respectively)(P<0.001,P=0.047,P=0.017).ConclusionUse of disposable DTL electrodes can prevent cross infection.Our results record the normal values of PhNR by age group in normal Chinese subjects and provide normal reference limits in clinical practice.更多还原