【摘要】 化学-酶法合成糖类具有立体选择性和区域选择性,逐渐成为糖类合成的主流.1-氟代糖作为糖基供体应用于化学-酶法合成反应,显示出越来越重要的作用,综述了1-氟代糖在糖基转移酶和糖苷酶催化的糖类合成中的应用.更多还原

【Abstract】 Chemoenzymatic methods have advantages over classical chemical methods in carbohydrate synthesis owing to stereoselectivity and regioselectivity. 1-Glycosyl fluorides, which act as glycosyl donors, are becoming increasingly important in the chemoenzymatic reactions. The application of 1-glycosyl fluo- rides in the glycosyl transferase and glycosidase-catalysed carbohydrate synthesis is reviewed in this paper.更多还原