节点文献
微波辐射下以1,3-二溴-5,5-二甲基乙内酰脲为溴代试剂合成3-溴黄酮
Microwave-Assisted Synthesis of 3-Bromoflavone Using 1,3-Dibromo-5,5-dimethyl-imidazolidine-2,4-dione as Brominating Agent
【摘要】 报道了在微波辐射下以1,3-二溴-5,5-二甲基乙内酰脲(DBDMH)为溴化试剂合成3-溴黄酮的新方法,系统考察了反应温度、时间及反应物配比对反应收率的影响.
【Abstract】 A new and efficient synthesis of 3-bromoflavone using 1,3-dibromo-5,5-dimethyl-imida- zolidine-2,4-dione as brominating agent under microwave irradiation was reported. The effects of molar ra- tio of reactants, reaction temperature and reaction time on the yields of product were investigated. Compared to the traditional heating method, microwave assisted synthesis shortened the reaction time from several hours to 15 min and gave better yields of products.
【关键词】 1,3-二溴-5,5-二甲基乙内酰脲；
3-溴黄酮；
微波辐射；
【Key words】 1,3-dibromo-5,5-dimethyl-imidazolidine-2,4-dione； 3-bromoflavone； microwave irradiation；
【Key words】 1,3-dibromo-5,5-dimethyl-imidazolidine-2,4-dione； 3-bromoflavone； microwave irradiation；
【基金】 国家自然科学基金(Nos.20432010,20476036,20172017);教育部跨世纪优秀人才资助计划;教育部重点科技项目;湖北省优秀创新群体(No.2004ABC002)资助项目.
- 【文献出处】 有机化学 ,Chinese Journal of Organic Chemistry , 编辑部邮箱 ,2006年05期
- 【分类号】TQ242
- 【被引频次】7
- 【下载频次】239