【摘要】 目的观察增厚的环咽后壁标本的肌纤维、弹性纤维、胶原纤维、网状纤维组织学的变化,探讨环咽肌切迹的形成机制。方法对13具标本(增厚的环咽后壁标本6例,正常的环咽后壁标本7例)行正常HE、Weigert及Gordon&Sweet染色,在光学显微镜下观察其肌纤维、胶原纤维、弹性纤维及网状纤维。结果增厚的环咽后壁的标本肌纤维形态异常,排列不规则,弹性纤维断裂呈不连续分布,胶原纤维和网状纤维增多,排列紊乱。结论肌细胞结构的破坏及结缔组织成分的异常与环咽肌切迹的发生密不可分。更多还原

【Abstract】 Objective To compare the histological differences between the normal and thicked posterior hypopharyngeal walls in order to understand the mechanism underlying the formation of the cricopharyngeal bar. Methods Transverse histological sections of the posterior hypopharyngeal walls from 13 adult cadavers(7 normal posterior hypopharyngeals and 6 thicken posterior hypopharyn-geals)were stained with HE, Weigert and Gordon & Sweet staining methods. Muscular, elastic, collagenous and reticular fibres of the sections were examined under a light microscope. Results Compared to that of the normal hypopharyngeal wall, the thickened posterior hypopharyngeal wall had abnormal morphology ,irregular arrangement of the muscle fibers, increased density, abnormal arrangement of collagen fibers and reticular fibers, and interrupted elastic fibers. Conclusion The pathogenesis of cricopharyngeal bar is closely associated with the disorganization of muscular and connective tissues fibres in the posterior hypopharyngeal wall. pharynge更多还原