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微囊藻毒素MC-LR对Raji细胞中Epstein-Barr病毒早期抗原的诱导
Epstein-Barr Virus Early Antigen Induction in Raji Cells by Microcystin-LR
【摘要】 研究微囊藻毒素-LR对EB病毒早期抗原的诱导作用。采用免疫酶法激活Raji细胞中EB病毒早期抗原的表达。微囊藻毒素-LR可以诱导Raji细胞中EB病毒早期抗原的表达,当与丁酸、巴豆油、TPA等促癌物协同作用时,其表达率明显增高。
【Abstract】 The effects of microcystin-LR on inducing Epstein-Barr virus early antigen(EBV-EA) are studied,and the expression of EBV-EA is activated by means of immunoenzymatic techniques.It is found that microcystin-LR not only induces the expression percent of EBV-EA but also markedly increases the expression percent of EBV-EA when in cooperation with tumor promoter such as n-butyrate,croton oil and 12-o-tetradecanoyl-phorbol-13-acetate(TPA).
【基金】 北京市人才强教基金资助项目(R05351)
- 【文献出处】 武汉科技大学学报(自然科学版) ,Journal of Wuhan University of Science and Technology(Natural Science Edition) , 编辑部邮箱 ,2006年04期
- 【分类号】R73-3
- 【被引频次】8
- 【下载频次】101