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H-FABP、MC4R、ADD1基因多态性在3个猪群中分布及其与肌内脂肪和背膘的相关研究

Distributions of Polymorphism of ADD1, MC4R, H-FABP Gene, Associated with IMF and BF in Three Populations in Pig

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【作者】 李长龙潘玉春孟和王子林黄雪根

【Author】 LI Chang-Long 1,3, PAN Yu-Chun1, MENG He1, WANG Zi-Lin2, HUANG Xue-Gen2 (1.Department of Animal Science, Shanghai Jiaotong University, shanghai 201101, China; 2.Center of Sutai Pig Breeding, Suzhou 215000, China;3.School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China)

【机构】 上海交通大学农业与生物学院苏州市苏太猪育种中心苏州市苏太猪育种中心 上海201101华东理工大学药学院上海200237上海201101苏州215000

【摘要】 具有不同遗传特性的猪种具有不同的肉质性状,尤其是地方品种和引进品种间在肉质性状上存在极大的差异。在已有的研究中,HFABP,MC4R,ADD1基因同肌内脂肪或背膘相关。利用梅山猪、苏太猪和杜×长×大猪为试验动物,研究上述3个基因的多态性分布和多态性同肌内脂肪和背膘的相关性。结果表明:3个基因的多态性分布在不同猪种间存在极显著的差异,这种差异可能是肌内脂肪(IMF)或背膘(BF)不同的主要原因之一。相关分析表明:HFABP和ADD1基因多态性同IMF有显著的相关,但是同BF没有显著的相关;MC4R基因的多态性同IMF和BF都有显著相关性。说明:HFABP和ADD1基因多态性有可能应用到提高IMF同时不影响BF的育种实践中。

【Abstract】 Different breeds of pigs varied in traits of meat quality, especially between local abroad varieties. Intramuscular fat content (IMF) and back fat thickness (BF) have extra difference between Chinese breeds and foreign breeds. We have known that polymorphism of H-FABP, MC4R and ADD1 gene associated relation with IMF or BF in recent research. The Meishan, Sutai and Duroc×Landrace×Yorkshair become experimental animal in this research. Result show three breeds have different IMF and BF because different distributions of polymorphism three genes. Meishan has particular genetic background, so it should be protected. The results of associated analysis show that the polymorphism of three genes was associated traits of IMF and BF, polymorphism of MC4R gene was not associated traits BF. The molecular marker can apply to pig breeding by molecular marker-assisted selection (MAS).

【关键词】 H-FABPMC4RADD1肌内脂肪背膘
【Key words】 H-FABPMC4RADD1IMFBF
【基金】 国家重点基础研究发展计划(973计划)项目(编号:2004CB117502);上海市科技兴农重点攻关项目(编号:沪农科攻关(2003)第011号)~~
  • 【分类号】S828.2
  • 【被引频次】115
  • 【下载频次】1038
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