【摘要】 目的:探讨经皮椎体成形术治疗椎体溶骨性转移癌的临床价值。方法:应用经皮椎体成形术治疗25例33个椎体的溶骨性转移癌。在C型臂X光机透视导向下经皮穿刺到病变椎体后注入骨水泥(3~8)ml。记录患者术前、术后24h、术后1周、术后1月的疼痛视觉模拟划线得分(VAS)。观察止痛效果和并发症。结果:33个椎体皆一次穿刺成功,穿刺成功率100%。1月后疼痛缓解程度为:完全缓解(CR)者6例(6/25),部分缓解(PR)者16例(16/25),轻度缓解(MR)者2例,无效(NR)者1例,总有效率(CR+PR)为88%(22/25)。患者术前与术后24h、术后1周、术后1月的VAS的得分之间差异有统计学意义(P<0.05)。PVP术后无1例椎体塌陷加重或发生新的骨折。除6例发生无症状的骨水泥渗漏外,无1例发生严重并发症。结论:经皮椎体成形术治疗椎体的溶骨性转移癌效果良好。更多还原

【Abstract】 Objective:To investigate the clinical efficacy of percutaneous vertebroplasty(PVP) for osteolytic vertebral metastatic carcinoma.Methods:33 osteolytic vertebral metastatic neoplasms in 25 cases were underwent PVP.Visual analogue scale point(VAS)(10-point scale) before vertebroplasty,24 hours after,one week and one month after vertebroplasty were recorded respectively.Pain relief and complications were observed.Results:A technical success of PVP was obtained in 100%.complete recovery(CR) and partial recovery(PR) were reached in 6 cases and 16 cases respectively after 30 days of the operation.The rate of pain relief was 88%.There are significant differences among the scores of VAS with different time points.No further or new vertebral compression occurred in all patients during the follow-up of 1～12 monthes.No major complications occurred in this series,except asymptomic bone cement leak around vertebrae.Conclusion:The clinical effection of percutaneous vertebroplasty for osteolytic vertebral metastatic carcinoma was satisfactory.更多还原