【摘要】 为了明确浙江省献血人群的HIV感染率,收集从1994至2004年间约660万献血者的筛检资料,应用ELISA初、复检筛选,应用免疫印迹法确证HIV感染。结果表明11年间,浙江省献血人群总体HIV感染率为0.0879/万,省内献血者感染率低于省外献血者感染率,男性感染者多于女性,近年来献血者HIV感染率呈明显增加趋势,且不同人群感染率的差异逐渐减小。结论在艾滋病低流行区域诸如浙江省,尽管未见输血传播HIV病例,但经输血传播HIV的趋势有扩大的风险。目前的筛检程序值得信赖,但仍需综合多种方法阻止HIV经血传播。更多还原

【Abstract】 To determine HIV prevalence among blood donors in Zhejiang Province from 1993 to 2004 years, almost 6 600 000 blood donors information were collected and analyzed. Every sample was screened for markers of HIV-1 and HIV-2 by using commercially available ELISA kits twice , and Western blot for confirmation if positive or suspicious result appeared. The results indicated that during the study period, prevalence rate of HIV infection was 0.85/1000 donors(0.085%), with the rising tendency from 1:600000 in 1995 to 1∶37500 in 2004. The prevalence of HIV infection in Zhejiang donors was significantly lower than that in donors of other provinces, prevalence of HIV infection in male was higher than that in female. In recent years, the prevalence of HIV in blood donors was obviously increased, but the difference among various populations began to reduce. It is concluded that in a low HIV prevalence area like Zhejiang province where no obvious AIDS occurred, risk for the expansion of the HIV epidemic was on the increase. Screening procedure used in transfusion services nowaday is reliable, but a comprehensive approach is required to make the blood more safe.更多还原