【摘要】 目的观察补阳还五汤对2型糖尿病肾病患者尿微量白蛋白的影响。方法将66例24h尿微量白蛋白30～300mg的2型糖尿病患者随机分为治疗组和对照组。治疗组用补阳还五汤治疗,对照组用黄芪注射液治疗。两组均以2周为1个疗程。观察临床疗效并检测血脂、血粘度、24h尿微量白蛋白及排泄率水平。结果治疗后,治疗组24h尿微量白蛋白及排泄率下降,血脂及血粘度下降,两组比较,差异有显著性或非常显著性意义(P<O.05或P<O.01)。结论补阳还五汤能降低2型糖尿病患者尿微量白蛋白。其作用机制可能是改善微循环障碍,降低血液粘稠度。更多还原

【Abstract】 Objective To observe the efficacy of Buyanghuanwu herbal decoctions on microalbuminur in noninsulin-dependent diabetes mellitus. Methods Sixty-six patients with noninsulin-dependent diabetes mellitus patients with 30～300 mg/24 h microalbuminur were randomly divided into the treated group (treated with Buyanghuanwu herbal decoctions) and the control group (treated with injection of Huangqi). The clinical efficacy was observed and levels of blood-fat, hemorheology and microalbuminur were determined. Results The levels of blood-fat, hemorbeology and microalbnminur were decreased in treated group. Comparison between the two groups showed significant difference (P <0.01). Conclusion Buyanghuanwu herbal decoctions can decrease the level of microalbuminur in patients of noninsulin- dependent diabetes mellitus, the mechanism might be promoting microcirculation disturbance and degrading blood viscosity.更多还原