【摘要】 目的:建立小儿止咳灵颗粒剂中黄芩苷的含量测定方法小儿止咳灵颗粒制剂中黄芩苷的含量。方法:采用高效液相色谱法测定,选定ODS-C18色谱柱(4.6 mm×250 mm,5μm),流动相:甲醇-0.4%磷酸(45∶55,v/v),检测波长280 nm。结果:本法线性范围为0.122~0.732μg(r=0.999 6),平均回收率为99.9%(RSD=0.56%)。结论:该方法简便、灵敏、准确、重现性好,可用于小儿止咳灵颗粒的质量控制。更多还原

【Abstract】 Objective: To establish a determination method of baicalin in Xiaoerzhikeling Granule.Method: HPLC,column: ODS-C₁₈（4.6 mm×250 mm,5 μm）,mobile phase: methanol-0.4% phosphoric acid（45∶55,v/v）,wavelength 280 nm.Result: The linear range was 0.122～0.732 μg（r=0.999 6） and recovery rate was 99.9%（RSD=0.56%）.Conclusion: This method is convenient,sensitive and accurate.And it can be used as standard quality control of Xiaoerzhikeling Granule.更多还原