【摘要】 目的:探讨儿童孤独症的病因、发病机理、诊断及早期干预。方法:对107例孤独症患儿的生物学因素(妊娠史、出生史、抽搐史、家族史)、家庭因素(父母性格、家庭教育情况)、病历主诉、感觉统合评定和辅助检查(脑CT、脑电图、听力测试、染色体)结果进行回顾性分析。结果:107例孤独症患儿中有异常妊娠史者27例,异常出生史者27例,异常家族史者19例,有抽搐史者20例。不良教育方式占61.7%。病历主诉中,语言交流障碍所占比例最大(73.8%)。感统失调者66例(61.7%)。常规脑电图、脑CT检查发现部分异常。染色体检查无特异性,脑干听觉诱发电位(BAEP)出现异常。结论:生物学因素异常及抽搐的发生等与孤独症的发病有密切关系;以语言发育迟缓及多动、注意力分散为主诉的儿童病例应考虑孤独症的可能;应及早进行干预并对患儿家长进行指导。更多还原

【Abstract】 Objective: To explore the pathogeny,mechanism and diagnosis of autism.Methods: One hundred and seven cases of autism children were studied about biologic factors(pregnancy,birth,seizure,family),family factors,chief complaint,assess of sensory integration and assistant examinations(CT,EEG,aural test,chromosome).Results: The abnormity in biologic factors was generally seen among the autism children and the language development disability was mainly the chief compliant(73.8%).Most of them sensory integrative dysfunction.BAEP may be abnormal.Conclusions: There was relationship between the abnormality of pregnancy,birth,family,seizure and the pathogeny of autism;the probability of autism should be paid attention to when the language development disability was the chief compliant;a good guide is necessary for these children′s parents.更多还原