【摘要】 目的探讨血液透析(HD)和腹膜透析(PD)治疗鱼胆中毒致急性肾功能衰竭(ARF)的疗效及并发症。方法将39例鱼胆中毒致ARF患者分成HD组(23例)和PD组(16例),在内科治疗基础上分别给予HD和PD治疗,进入多尿期后减少透析次数,当血肌酐降至200~250μm o l/L时停止透析。结果HD组患者的血尿素氮(BUN)、血肌酐(Scr)、血钾(K+)、二氧化碳结合力(CO2CP)和肝功能(ALT)恢复正常的时间均明显短于PD组(P<0.05),HD组患者的少尿期持续时间、消化道症状持续时间和平均住院时间也短于PD组(P<0.05);但HD组患者透析中的并发症发生率明显高于PD组(P<0.05);而两组患者的预后差异无统计学意义(P>0.05)。结论HD和PD均是治疗鱼胆中毒致ARF的有效方法,HD优于PD。更多还原

【Abstract】 Objective To explore the therapeutic effects and complic ations of hemodialysis（HD） and peritoneal dialysis（PD） in the treatment of acute renal failure（ARF）induced by fish gall poisoning.Methods Thirty-nine cases of ARF caused by fish gall poisoning were divided into HD group（23 cases） and PD group（16 cases）,in which HD or PD were administered on the basis of conventional internal medical treatment.The times for dialysis were reduced during polyuria period and stopped when the blood creatinine level fell down to 200-250μmol/L.Results The time needed to return the normal levels of blood urea nitrogen（BUN）,serum creatinine（Scr）,blood potassium,CO₂-combing power,alanine aminotransferase（ALT） was significantly shorter in HD group than PD group（P<0.05）.The duration of oliguria and digestive tract symptoms and the average stay in hospital were shorter in HD group than PD group（P<0.05）;however,the complications were higher in HD group than PD group（P<0.05）.The prognosis was similar in the two groups（P>0.05）.Conclusion Both HD and PD are effective protocols for treatment of ARF caused by fish gall poisoning,in which HP is superior to PD.更多还原