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职业性铅接触对作业工人血微量元素的影响

THE INFLUENCE OF EXPOSURE TO LEAD ON LEAD WORKERS’ MICROELEMENTS OF BLOOD

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【作者】 闫娟王培席杨跃林修良昌王永伟

【Author】 YAN Juan,YANG Yue-lin,WANG Pei-xi,et al.Department of Occupational health,West China School of Public Health,Sichuan University,Chengdu,610041.

【机构】 四川大学华西公共卫生学院劳动卫生教研室河南大学公共卫生研究所四川大学华西公共卫生学院卫生统计教研室四川大学华西公共卫生学院劳动卫生教研室 成都610041成都

【摘要】 目的:探讨职业性铅接触对工人血中微量元素的影响。方法:整群抽取成都某蓄电池厂铅作业工人79名(观察组)、非铅作业工人69人(对照组),对其进行血清Fe、Zn、Ca、Pb-B、Pb-U、δ-ALA、ZPP测定,并进行相关和多因素回归分析。结果:①观察组的Pb-B、Pb-U、δ-ALA、ZPP均大于对照组。②观察组的血清Fe、Zn、Ca均低于对照组。③影响血清Fe水平的因素有是否接铅、Pb-U、ZPP、锻炼;影响血清Zn水平的因素有是否接铅、Pb-B、ZPP。结论:职业性铅接触对作业工人的血清铁和血清锌影响较大,应对接触铅的工人提供健康保护措施,切实保护工人的健康与安全。

【Abstract】 Objective:To study the changes of microelements of blood caused by occupational lead exposure.Methods:Participants in this study includes the workers who exposed to lead in a lead-acid storage cell factory(n=79)and a factory who had no history of exposure to lead in Chengdu city(n=69).Serum iron(Fe),serum zinc(Zn),serum calcium(Ca),Blood lead(Pb-B),Urinary lead(Pb-U),aminolevulinic acid(ALA)and zinc protoporphyrin(ZPP)level were measured.The correlation analysis and multiple factor regression analysis were used.Results:The Pb-B,Pb-U,δ-ALA and ZPP of observe groups are all higher than control group.②The Fe-B,Zn-B,Ca-B of observe groups are all lower than control group.③The influence factor of serum iron are exposure to lead,Pb-U,ZPP and exercise;The influence factor of serum zinc are exposure to lead,Pb-B,ZPP.Conclusion:Occupational lead exposure influence the workers’ serum iron,serum zinc obviously.The occupation protection should be strengthened,and the worker’s working condition should be improved to protect the workers’ health and safe.

【关键词】 铅接触血清铁血清锌
【Key words】 lead exposureserum zincserum iron
  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2006年10期
  • 【分类号】R131
  • 【被引频次】3
  • 【下载频次】62
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