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凤鸣藤茶的免疫毒理学评价

EVALUATION ON IMMUNO TOXICOLOGY OF FENG MING AMPELOPSIS GROSSEDENTATA EXSTRACT

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【作者】 伍杨林平邓明会

【Author】 WU Yang,LING Ping,DEN Ming-hui.Medical school of Hubei Institute for Nationalities,Enshi,445000.

【机构】 湖北民族学院医学院微寄免教研室湖北民族学院医学院微寄免教研室 湖北445000湖北445000

【摘要】 目的:观察凤鸣藤茶对小鼠免疫功能的影响。方法:将昆明种小鼠随机分为对照组、藤茶组(2.7 g/kg.bw.4.5 g/kg.bw.9 g/kg.bw 3个剂量组),喂养30 d,比较各组小鼠免疫功能改变情况。结果:与对照组比,藤茶组小鼠免疫器官脏体比,自然杀伤(NK)细胞活性、吞噬细胞功能显著增强,溶血空斑数明显增加,小鼠DTH肿胀度各组小鼠间差异无统计学意义。结论:凤鸣藤茶具有增强小鼠免疫功能的作用,免疫毒理学方面的评价是安全的。

【Abstract】 Objective:To observe the effect of Feng Ming Ampelopsis grossedentata on immunity functions of mice.Methods:Kun Ming mice were divided into control group and Ampelopsis grossedentata group(2.7 g/kg·bw;4.5 g/kg·bw;9 g/kg·bw three dosage groups)After feeding for 30 days,immunity function change of each group were compared.Results:Ampelopsis grossedentata group was compared with control group.In ampelopsis grossedentata group.Organs-body ratio of immuno organs,NK cell gactivity,and phagocyte function were obviously strengthened(P<0.01),plague forming cell assay obviously increased.DTH swollen degree of mice in every group were not significantly different.Conclusion:Feng Ming Ampelopsis grossedentata have the effect of increasing immunity functions on mice,and its evaluation of immuno-toxicology is safe.

  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2006年07期
  • 【分类号】R285
  • 【被引频次】13
  • 【下载频次】149
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