【摘要】 目的:观察加减瓜蒌薤白半夏汤对大鼠急性心肌缺血模型血流动力学的影响。方法:结扎SD大鼠左冠状动脉前降支造成实验性心肌缺血模型,应用多导电生理监测仪监测血压(BP)、左室舒张末压力(LVEDP)、左室等容收缩期最大上升速率(+dp/dtmax)、左室等容舒张期最大下降速率(dp/dtmax)。结果:大剂量中药可抑制心肌缺血所致LVEDP升高和BP、+dp/dtmax、-dp/dtmax的降低(P<0.01)。结论:加减瓜蒌薤白半夏汤可显著改善缺血心肌的血流动力学指标。更多还原

【Abstract】 Objective:To observe the blood kinetic effects on experimental myocardial ischemia of rat caused by adjusted T.kirilowii maxim and P.ternata(Thunb.)breit medicinal broth.Methods:Ligating the front-inferior branch of the left coronary artery of the SD rat to create a model of experimental myocardial ischemia and 24-electrophy silolgical instrument were used to monitor BP、LVEDP、(+dp/dtmax)and(dp/dtmax).Results:Large amount of Chinese traditional medicine can choke back the increase of LVEDP and the decrease of BP、(+dp/dtmax)and(dp/dtmax)which are all caused by myocardial ischemia.Conclusion:Adjusted T.kirilowii maxim and P.ternata(Thunb.)breit medicinal broth can notablely improve the blood kinetic change of myocardial ischemia.更多还原