【摘要】 目的:研究攀枝花地区野生番石榴叶水提取物降血糖作用。方法:雄性昆明种小鼠,诱导葡萄糖性、肾上腺素性和链脲佐菌素性高血糖,受试物灌胃处理。测定处理后小鼠尾静脉血血糖,比较给予受试物前后血糖水平的变化。结果:番石榴叶水提取物不同程度降低外源性高血糖、拮抗应激性葡萄糖升高,明显降低糖尿病小鼠血糖水平,改善糖尿病小鼠糖耐量。结论:攀枝花地区野生番石榴叶水提取物能够抑制多种因素导致的血糖升高,具有明显的降血糖作用。更多还原

【Abstract】 Objective:To study the role of water-soluble extract from Psidium guajava leaves in decreasing blood glucose.Methods:High-level blood glucose models were made by male Kunming mice administrated with intraperitoneal glucose,subcutaneous adrenaline and intraperitoneal streptozotocin,respectively.Blood glucose concentration was measured after oral administration.All available indexes were compared statistically.Results:Water-soluble extracts showed the potential of resisting the rising of blood glucose which induced by exogenous glucose and adrenaline to various extent.Furthermore,water-soluble extract decreased blood glucose significantly and improve OGTT(oral glucose tolerance test)in STZ-induced diabetic mice.Conclusion:The study demonstrate that water-soluble extract from Psidium guajava leaves have the effect on lowing blood glucose.更多还原