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河南省某地艾滋病母婴传播危险因素的病例对照研究

Case control study on the key risk factors of HIV mother-to-child transmission(MTCT)in a city of Henan province

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【作者】 施建春王卫民李雷何景阳

【Author】 SHI Jian-chun,WANG Wei-min,LI Lei,et al.(Nanyang Center for Disease Prevention and Control,Nanyang,Henan 473002,China)

【机构】 南阳市卫生防疫站河南省疾病预防控制中心 河南南阳473002河南南阳473002郑州452003

【摘要】 目的为探讨影响艾滋病母婴传播的主要危险因素。方法对南阳市艾滋病病毒(HIV)抗体阳性的19~49岁育龄妇女及其生育情况进行现场调查,对艾滋病母婴传播的可能危险因素进行病例对照研究。结果促进母婴传播发生的危险因素有母亲怀孕时机会性感染的出现情况(OR=52.25)、生育时合并性病(OR=6.54)、头胎(OR=5.48)以及早产儿(OR=4.13);能够减少母婴传播发生的因素有:择期剖宫产(OR=0.12)、人工喂养(OR=0.08)、产程<9小时(OR=0.07)。结论采取正确安全的母婴阻断措施,可以有效预防艾滋病母婴传播。

【Abstract】 Objective To study key risk factors of HIV mother-to-child transmission(MTCT).Methods Women aged 19~49 years with HIV positive in the city were investigated for their child reproduction status including pregnancy,delivery and breast feeding etc and a case-control study was then conducted for possible risk factors of MTCT.Results The risk factors of MTCT were opportunistic infection present during pregnancy(OR=52.25),complication with STD during pregnancy and childbirth(OR=6.54),premature infant(OR=4.13)and first born infant(OR=5.48);The protective factors were cesarean section on selected days(OR=0.12),artificial feeding(OR=0.08)and shortened length of delivery(OR=0.07).Conclusions Through appropriate and safe interventions,the HIV mother-to-child transmission could be prevented effectively.

【关键词】 艾滋病母婴传播影响因素
【Key words】 AIDS/HIVMTCTInfluencing factorsCase-control study
  • 【文献出处】 中国艾滋病性病 ,Chinese Journal of AIDS & STD , 编辑部邮箱 ,2006年05期
  • 【分类号】R512.91
  • 【被引频次】14
  • 【下载频次】144
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