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乌鲁木齐市静脉吸毒人群HIV感染及危险因素研究

Cross-sectional survey of human immunodeficiency virus injection among injection drug users in Urumchi,Xinjiang Uigur Autonomous Region,China

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【摘要】 目的了解乌鲁木齐市静脉吸毒人群艾滋病病毒(HIV)感染情况。方法于2004年9~10月,调查戒毒所等机构内静脉吸毒人群的社会人口学、静脉吸毒和性行为方式,并采集血样检测HIV和梅毒抗体。结果在调查的静脉吸毒者509人中,HIV感染率为37.3%(190人)。多因素logistic回归模型分析结果显示,维族(OR 7.91,95%CI 4.92~12.72)、近3个月内共用注射器具静脉吸毒5次及以上(OR 2.61,95%CI 1.48~4.60)和静脉吸毒5年以上(OR 1.64,95%CI 1.09~2.48)与HIV感染关系有统计学意义。结论乌鲁木齐市静脉吸毒人群HIV感染率高,高危行为普遍,需采取有效的措施来控制HIV的传播流行。

【Abstract】 Objective To investigate the prevalence of HIV and risk factors among injection drug users(IDUs)in Urumchi,Xinjiang Uigur Autonomous Region,China.Method From September to October 2004,a total of 509 IDUs in detoxification or re-education centers were interviewed by trained health workers.Each participant who injected drug for 3 months before incarceration completed an informed consent and a structured questionnaire with an interviewer,including demographic characteristics,patterns of sharing injection equipment and sexual activities.Blood sample were also collected to test for antibodies against HIV and syphilis.Chi-square test and multivariate analyses were used to identify potential risk factors for HIV infection.Result Among the total 509 participants,HIV prevalence was 37.3%(190/509).Multivariate logistic regression analysis showed that Uigurs who shared injection equipment for 5 times or more(OR=7.91;95%CI,4.92~12.72)in the past three months(OR=2.61;95%CI,1.48~4.60)and used drugs for more than 5 years(OR=1.64;95%CI,1.09~2.48)were independently associated with HIV infection.Conclusion The HIV prevalence was high and risk behaviors related to HIV infection were common among IDUs in Urumchi.There are urgent needs to carry out health education and intervention to control local HIV transmission.

【基金】 卫生部艾滋病防治应用性研究项目(WA2003-13);国家十五科技攻关项目(2004BA719A01、2004BA719A02);国家自然科学基金项目(30571612、10501052)
  • 【文献出处】 中国艾滋病性病 ,Chinese Journal of AIDS & STD , 编辑部邮箱 ,2006年04期
  • 【分类号】R512.91
  • 【被引频次】21
  • 【下载频次】95
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