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干细胞可塑性争议及分化假说
Plasticity controversy and differentiation hypotheses of stem cells
【摘要】 对有关干细胞可塑性的不同观点进行了概述,并关注了干细胞潜能和细胞表型多样性传统观点上的争议,讨论了在当前公认动物模型上观察到的干细胞可塑性现象,并对分化细胞发生细胞表型转变的试验性观察结果进行了总结。
【Abstract】 The present review not only examined the different points of stem sell plasticity focused on the controversies of traditional views on stem cell potentiality and cell type variety,but also discussed the phenomenon of plasticity observed in the wildly accepted animal models.In addition,the experimental results derived from research of trans-differentiation of somatic cells were summarized.
【关键词】 干细胞;
可塑性;
横向分化;
细胞融合;
细胞异质性;
【Key words】 stem cell; plasticity; transdifferentiation; cell fusion; heterogeneity;
【Key words】 stem cell; plasticity; transdifferentiation; cell fusion; heterogeneity;
【基金】 国家高技术研究与发展计划项目(863计划)(2002AA216161)
- 【文献出处】 西北农林科技大学学报(自然科学版) ,Journal of Northwest Sci-Tech University of Agriculture and Forestry(Natural Science Edition) , 编辑部邮箱 ,2006年10期
- 【分类号】Q2-0
- 【被引频次】1
- 【下载频次】101