【摘要】 目的测定褐家鼠对抗凝血灭鼠剂溴敌隆的敏感性。方法在实验室作无选择性摄食试验。将试鼠雌雄分开,随机分组,按5个不同食毒期摄食0.000 2%溴敌隆毒饵。用B liss计算机程序,计算不同食毒期与对应死亡率之间关系。结果褐家鼠对溴敌隆的敏感性没有性别差异(Pb>0.05,PLFP50>0.05),故雌雄数据合并计算,得y=2.14+6.30x,LFP50、LFP99及其95%置信限分别是2.85(2.48~3.27)、6.68(4.87~9.16)。结论按WHO修订以致死99%敏感靶标鼠种的食毒期(LFP99)取整天数作为抗药性检验标准,本地区褐家鼠对0.000 2%的溴敌隆毒饵食毒期超过7 d存活为产生抗药性。更多还原

【Abstract】 Objective To study susceptibility tests of Rattus norvegicus in Zhanjiang to Bromadiolone. Methods Firstly hiving off the males and females,then dividing into groups at random.No-chice were fed the Bromadiolone bait at concentration of 0.000 2% at five different feeding days.Using Bliss software,statistics their relevant to death rates at the different feeding days. Results By statistical analysis,the Bromadiolone susceptibility was of no sex significant difference(P_b>0.05,P_LFP50>0.05),obtaining the quality（y=2.14+6.30x）.On combination of the sex data,LFP₅₀ and LFP₉₉ and its 95% fiducial limits for Rattus norvegicus were 2.85（2.48～3.27）,6.68（4.87～9.16） days respectively. Conclusion According to WHO,the revising standard that the days of LFP₉₉ is made the mark.The local Rattus norvegicus were fed the 0.000 2%,the bait making the standard of resistance in excess of seven days.更多还原